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Reform Needed at FDA?; Prince William's Last Days of College

Aired November 19, 2004 - 13:30   ET

THIS IS A RUSH TRANSCRIPT. THIS COPY MAY NOT BE IN ITS FINAL FORM AND MAY BE UPDATED.

THIS IS A RUSH TRANSCRIPT. THIS COPY MAY NOT BE IN ITS FINAL FORM AND MAY BE UPDATED.


CAROL LIN, CNN ANCHOR: Topping the headlines this hour, violence in Iraq, a suicide car bomb in Baghdad. Five people dead. A gun fight at a mosque. Two dead. And a mortar round lands in the Green Zone. U.S. military officials believe insurgents who escaped Falluja are now operating elsewhere.
A group that opposes the government of Iran is adding volume to accusations that Tehran is actively pursuing a nuclear weapon. Iran says that's not true. Now the United Nations says it needs to look into this. Well, it is very tricky diplomatically for the United States because the group making the charges is on Washington's terrorism list.

So just what did kill Yasser Arafat? Well, his nephew intends to find out. Nasser al-Kidwa, also the current Palestinian representative to the United Nations, is in Paris today reviewing his uncle's medical records. French officials never revealed the exact cause of the Palestinian leader's death, insisting that information can only be given to a family member.

And resting comfortably, that is the word from doctors tending to National Security Adviser Condoleezza Rice. She had surgery this morning, a uterine fibroid embolization. According to the doctors at Georgetown University Hospital, the procedure was pretty unremarkable. The patient is A-OK. She may actually even return to work on Monday.

MILES O'BRIEN, CNN ANCHOR: The company that makes the pain medication Vioxx got no slack yesterday on Capitol Hill. The same for the federal agency that regulates the prescription drug market in this country. Merck CEO Raymond Gilmartin told a Senate Finance Committee hearing that his company yanked Vioxx immediately after the health risks of the drug were proven.

Now the report said he knew about possible problems for a year, however, and still kept the drug out there any way. Merck's relationship with the Food and Drug Administration also raising eyebrows with some senators and with physicians in the field.

(BEGIN VIDEO CLIP)

DR. JOHN ABRAMSON, AUTHOR, "OVERDOSED AMERICA": The problem is that the division of the FDA that approves new drugs, more than half of its budget comes from the drug companies -- comes from user fees from the drug companies. And the part of the FDA that oversees drug safety is within that division. So there's a structural problem. There's not enough separation in the FDA from the drug companies.

(END VIDEO CLIP)

O'BRIEN: So what about that relationship? Drug companies need the FDA's blessing. The FDA needs the drug company's money. That has been business as usual for quite some time now. There's talk now that a change may be due. Here is medical correspondent Elizabeth Cohen.

(BEGIN VIDEOTAPE)

ELIZABETH COHEN, CNN MEDICAL CORRESPONDENT (voice-over): The Vioxx hearings have left many people wondering how could a drug that causes heart attacks get approved by the Food and Drug Administration? Doesn't the United States have the best, most rigorous drug approval process in the world? The answer to that question has to do with a common misperception.

Many people think it is the FDA that conducts studies on drugs before they go on the market. In fact, the pharmaceutical companies do the studies on their own drugs. The FDA just reviews their data. And more and more observers, such as Dr. Jerry Avorn, author of the book "Powerful Medicines" thinks this system doesn't make much sense.

DR. JERRY AVORN, HARVARD MEDICAL SCHOOL: I think we need to have a more vigilant and aggressive FDA.

COHEN: One problem, he says, the salaries of the FDA reviewers are paid in part by the drug companies. The pharmaceutical industry spends hundreds of millions of dollars on so-called user fees to the FDA. And some say that makes for too cozy of a relationship.

AVORN: And it really needs to be a tough agency that is going to really ask some very demanding questions because we're talking about chemicals that people put into their body that can alter their health for good or for ill.

ALAN GOLDHAMMER, PHARMACEUTICAL IND. SPOKESMAN: We have seen these allegations of the coziness between the industry and the Food and Drug Administration. We think that they really are not true.

COHEN: In fact, the pharmaceutical industry says...

GOLDHAMMER: The process for approving new drugs by the Food and Drug Administration is working quite well.

COHEN: The industry points out that it spends years testing each drug on animals and then on humans. And the FDA then takes about a year to review those studies and often asks for even more data. But others say that pulling Vioxx and other drugs off the market because of safety worries is proof that somehow somewhere the system is falling short.

Elizabeth Cohen, CNN, Atlanta.

(END VIDEOTAPE)

O'BRIEN: Keep it right here on CNN for more on Vioxx, the FDA, it's relationship with drugmakers and the blame game. All of that in our next our of LIVE FROM.

LIN: All right. Meanwhile, a quick look at what is making news across America right now. Mental issue? Road rage? Who knows. Police are trying to piece together what led a man to walk into the Gateway Mall in St. Petersburg, Florida, with a gun yesterday. He opened fire, killing two people, wounding a third, then turned the gun on himself. Investigators are stumped.

Bizarre. A Massachusetts woman on her deathbed confesses to a killing and points police to the body. The victim, her husband, 14 years ago. The confessor died last week. Police did find the body. Identification is still forthcoming.

A hearing today in a suburban Atlanta courtroom for two 13-year- old girls. The charge is assault with intent to commit murder. Authorities say the two teens served up some poison-laced cake to a dozen classmates, all of whom got sick.

And is this a deadly weapon? Well, it almost was. Police say a car load of teenagers threw a 20-pound frozen turkey into Long Island traffic. It went through the windshield of another car and hit the driver in the face. A woman is now in critical condition. Six teenagers arrested and the list of charges is pretty long.

This may be hard to believe as well, but there is a downside to being the richest man in the world. Poor Bill Gates. Also, he has the uneviable reputation of being the most spammed guy in the world. He's inundated with up to 4 million -- that's right, you heard me, 4 million e-mails every day, most of them junk. But, unlike most of us, the software magnate has almost an entire department to filter out unwanted e-mails. A jobs program.

All right. Bill Gates can't be very happy about that either, but did you know that a browser war was being waged? The diehard Netscapers and Explorer fans among you probably do know there's a new kid in town and it is taking aim at the big two.

Daniel Sieberg is our technology correspondent, he's here to smarten us up on Firefox and why we're even talking about it today. Isn't more better, Daniel?

DANIEL SIEBERG, CNN TECHNOLOGY CORRESPONDENT: Well, to some people it definitely is, Carol. And the first rounds have been fired in this latest browser war. And the question now is how it will reshape the online landscape. Now let's take short trip back in time. Go with me here if you will.

Remember, Netscape? It is still around. It's part of our parent company, Time Warner. But you'll recall that Netscape used to dominate the browser market in the early days of the Web. And along came Bill Gates and Microsoft. Some years passed. We had some rather controversial bundling of software from Microsoft. And by the late 1990s, Internet Explorer had reduced Netscape to really just a few dedicated users.

OK. Fast forward to today and the fox in Microsoft's henhouse. Firefox is a new browser from a nonprofit offshoot of Netscape called Mozilla. It promises to be faster, easier and safer, when we're talking about viruses and spyware, than IE, or Internet Explorer. Oh, and by the way, it is free.

But it still isn't perfect with every Web site out there. And that's because some places designed their pages to be read on Internet Explorer. So some growing pains to work out. Is Microsoft taking notice? You bet. Are they worried? Well, they're not exactly pulling out all the stops, let's say, but it has been a long time since the company started firing shots in the browser market.

Microsoft is a huge target. So let's lay out the battle lines here. Let's see how are drawn. Microsoft still with a huge share of the market, obviously at 93 percent. The overwhelming majority of people out there use Internet Explorer. But Firefox, I know 3 percent sounds small, but Firefox claims that about 4 million people have downloaded their software in the last month or so and that number is still going up.

Netscape hanging around. Safari, which is Apple's browser software, and Opera, which is actually based in Norway, they are also vying for more of the cybersurfing share. Netscape has a new product coming out, by the way, and Safari getting some good reviews.

At this point the question isn't so much will Microsoft win but how will this competition force some changes in how we surf the Web. And you know, some experts say that's overdue. They say that Microsoft got a bit complacent after IE dominated the scene. It's time that another company came along to get things fired up and that may be Firefox -- Carol.

LIN: That's why we like competition, America.

SIEBERG: Exactly. The consumer always wins.

LIN: There you go, hopefully. Daniel, thank you.

O'BRIEN: Excelling at your job and your life? Up next on LIVE FROM, how to find profit, passion and purpose while on the road to success.

LIN: All right. Later, the princely pupil, a rare glimpse at college life of Prince William, which is about to come to an end.

(COMMERCIAL BREAK)

O'BRIEN: All right. Ever thought of your job as an endless cycle of paydays, a soloist climb to the top, making your deal with the devil? Everyday. Not really.

Kevin Salwen and Anita Sharpe are here to talk about how to add a little punch to your paycheck, so to speak. They are the founding editors of a magazine called "Worthwhile." It's a new personal business magazine, focusing on the quest for heart and soul of work. It just hit newsstands. You might not be able to find it, because apparently, it's flying off the shelves. Welcome. Glad things are going well.

ANITA SHARPE, "WORTHWHILE" MAGAZINE: Thank you. Thank you.

O'BRIEN: Glad things are going well.

SHARPE: They are. We're really encouraged.

O'BRIEN: Tell us, just give us a quick backstory on this, the idea of the magazine. You obviously saw a little niche here. Give people a sense of what the magazine was all about and where the idea came from.

SHARPE: The idea, sort of the soundbite for the magazine really is, it's about enlightened leadership and impassioned careers, and Kevin and I starting talking about it more than a year ago, and looking around and saying, there's really not a magazine that addresses what we do where we spend more than half of our lives, which is at work, and they're plenty of business magazines, but this is really more of a -- we like to call it sort of a career life summit.

O'BRIEN: You're both business journalists, "Wall Street Journal" background, and publications like "The Wall Street Journal" cover the business world wonderfully, but they miss this aspect of it, don't they?

KEVIN SALWEN, "WORTHWHILE" MAGAZINE: Well, you mentioned in your intro, it's really about heart and soul. And think about it, we wake up, we spend 50 hours a week doing our careers, doing our work. It's intensely important to us. We don't want to read profiles of other companies. We want to read things that go right to our core, and that's what "Worthwhile" is really focusing on.

O'BRIEN: Now, you -- on the cover here, you have the guys, the "life is good" guys. How are you selecting people? What are you looking for as you look at people to put in for content into your magazine?

SHARPE: Well, we're looking for people whose stories are likely to inspire, stories about people who are doing things both inside big corporations, outside, who are loving what they do. So you can read the story and think, ah, that person is who I want to be. And also, we're trying to find real people, people that not just sort of pie-in- the-sky type careers, but real stuff.

O'BRIEN; That's a good point, because I'm sure there are a lot people who would pick up this magazine, Kevin, in the Dilbert world, if you will, and say, you know, that's great, that sounds like fun, but I can't get there from here.

SALWEN: Right, and we understand that in every single, magazine we have to have a string of practical ideas that people can execute today, tomorrow, this week, whatever. And so, in addition to the inspiration, yes, we have these role models out there, that are out there that are out there sort of, you know, hey look, I can beat that, or I can emulate that. But at the same time, we have to give people real tools to be able to do it. There's a section in the magazine actually called "Toolbox" that is all about that.

O'BRIEN: All right, we selected a couple toolbox items, as a matter of fact. You have segued beautiful to this segment.

SALWEN: I'm good at that.

O'BRIEN: Focusing our passion is one of them, and it gives a series of steps. Here are the top six, create your own compass. What does that mean, create your own compass?

SALWEN: Well, it's really digging down into sort of the things that trigger you. What are things that actually -- Kurt Rosengrand (ph), who wrote that piece, focuses on what he calls the passion core. And it's really starting to examine, what are the things that motivate me. You do it so easily in your personal life and in your social life. You automatically gravitate to the things that inspire you and set you on fire. Why not do it in the 50 hours a week you're working?

O'BRIEN: And can you say "passion core" on TV? Is that OK?

SALWEN: It's just did.

O'BRIEN: It's cable.

All right, sculpt and scan, what is that all about?

SHARPE: Sculpt and scan. You really have to look at the broad field of what's out there, but at the same time, you have to sort of narrow it down. You have to keep both perspectives in mind all of the time. You have to be picking up clues, and at the same time, you have to be focusing.

O'BRIEN: Focusing is one of the hardest things, I think, for a lot of people. Now where is the fit? What does that mean?

SALWEN: Well, it's very easy for me to say, you know, I want to be a NASA astronaut, but I really don't have the tools to do that. And you've got to be able to sort of be practical about this. You know, what we were talking about before, that practicality element. If you're going to do something that really sets you on fire, it's got to be something within your core.

O'BRIEN: And having seen you on the (INAUDIBLE), I do know you will never make it to the astronaut car. OK, whittling them down. That seems fairly self evident, but going about that, I guess, is the key, and finding the tools and sort of figuring out what's most important to you is the hardest part, right?

SHARPE: Right, right, well, you have to take all of these clues, and then you have to fit them to your talents, and you have to -- and so you have to take 12 things and really get it down, ultimately, to one or two or three.

O'BRIEN: And then map it and hit the road. Those seem self- evident. I guess the key here is that what you have to view this pursuit as a career unto itself, don't you? SHARPE: Right, right. Absolutely. I mean, it's not like you have to quit your job and devote full time to it, but it's an important thing. You have to...

O'BRIEN: Don't be so accidental about it, in other words.

SALWEN: No, you know, great things happen accidentally when you're in the right place, and when you've done the work to get you to the point where you can structure, you know, your own career, things come to you, and all of a sudden, hey, it's the great opportunity, and you've got it.

O'BRIEN: Chance favors of the pared mind, I think is the expression.

SHARPE: Absolutely.

O'BRIEN: Anita Sharpe -- I didn't make that up. Anita Sharpe, Kevin Salwen. The magazine is "Worthwhile," and if you see it on a newsstand, well worth your while. We invite you to pick it up and check it out. Thanks for your time. Good luck with the magazine.

SHARPE: Thank you.

O'BRIEN: All right. He's just a year away from entering public life. Up next on LIVE FROM, a look at college life for Prince William in a rare interview.

(COMMERCIAL BREAK)

LIN: The second in line to the British thrown would be scanning the help-wanted ads next year. Prince William, son of Charles and Diana, finishes university in a few months, but has yet to decide what to do with himself.

CNN's Diana Muriel has been taking a look at his options.

(BEGIN VIDEOTAPE)

DIANA MURIEL, CNN ANCHOR (voice-over): An ordinary student on his way to lectures, but Prince William is no ordinary student. He is second in line to the British throne. These pictures offer a glimpse of the young prince's life at university. Like many students, he's behind in his courses.

UNIDENTIFIED MALE: And what about the glacial essay?

PRINCE WILLIAM: Yes, that hasn't materialized at all yet. I've done a few bits of reading.

MURIEL: Still, his geography tutor admires his princely pupil.

CHARLES WARREN, PRINCE WILLIAM'S TUTOR: He's worked really hard not to let his presence disrupt his fellow students existence, and keep a low profile, pull his weight and become one of the crowd. So no one lifts an eye brown these days when he walks around. MURIEL: That's not entirely true. William still turns heads, but he has a strong and supportive group of friends.

Next May, the 22-year-old prince leaves the same confines of his Scottish university. William admits he hasn't decided what he wants to do, but the army is a possibility.

PRINCE WILLIAM: If I was going join the army, which out of all the armed forces, it would be probably my favorite, or to do something different, (INAUDIBLE) to join the Navy, and (INAUDIBLE) something different, and the army, it's obviously a lot more in the spotlight of (INAUDIBLE).

MURIEL: What he does know is that life outside of university will never be as private again, and that could be tough.

PRINCE WILLIAM: Deep down, I have a, you know, pretty normal life. I'm not really taken for sort of fanfare and excitement and things like that, but I rise to the occasion when I need to.

MURIEL: William plans to take time off to travel when he leaves school next year, while he decides what to do next.

Diana Muriel, CNN, London.

(END VIDEOTAPE)

(STOCK MARKET REPORT)

LIN: Also coming up in the second hour of LIVE FROM, academic achievement. This woman was one of the top in her class, but now, more than 50 years later, she finally gets the credit she deserves.

LIVE FROM's hour of power begins right after this.

TO ORDER A VIDEO OF THIS TRANSCRIPT, PLEASE CALL 800-CNN-NEWS OR USE OUR SECURE ONLINE ORDER FORM LOCATED AT www.fdch.com


Aired November 19, 2004 - 13:30   ET
THIS IS A RUSH TRANSCRIPT. THIS COPY MAY NOT BE IN ITS FINAL FORM AND MAY BE UPDATED.
CAROL LIN, CNN ANCHOR: Topping the headlines this hour, violence in Iraq, a suicide car bomb in Baghdad. Five people dead. A gun fight at a mosque. Two dead. And a mortar round lands in the Green Zone. U.S. military officials believe insurgents who escaped Falluja are now operating elsewhere.
A group that opposes the government of Iran is adding volume to accusations that Tehran is actively pursuing a nuclear weapon. Iran says that's not true. Now the United Nations says it needs to look into this. Well, it is very tricky diplomatically for the United States because the group making the charges is on Washington's terrorism list.

So just what did kill Yasser Arafat? Well, his nephew intends to find out. Nasser al-Kidwa, also the current Palestinian representative to the United Nations, is in Paris today reviewing his uncle's medical records. French officials never revealed the exact cause of the Palestinian leader's death, insisting that information can only be given to a family member.

And resting comfortably, that is the word from doctors tending to National Security Adviser Condoleezza Rice. She had surgery this morning, a uterine fibroid embolization. According to the doctors at Georgetown University Hospital, the procedure was pretty unremarkable. The patient is A-OK. She may actually even return to work on Monday.

MILES O'BRIEN, CNN ANCHOR: The company that makes the pain medication Vioxx got no slack yesterday on Capitol Hill. The same for the federal agency that regulates the prescription drug market in this country. Merck CEO Raymond Gilmartin told a Senate Finance Committee hearing that his company yanked Vioxx immediately after the health risks of the drug were proven.

Now the report said he knew about possible problems for a year, however, and still kept the drug out there any way. Merck's relationship with the Food and Drug Administration also raising eyebrows with some senators and with physicians in the field.

(BEGIN VIDEO CLIP)

DR. JOHN ABRAMSON, AUTHOR, "OVERDOSED AMERICA": The problem is that the division of the FDA that approves new drugs, more than half of its budget comes from the drug companies -- comes from user fees from the drug companies. And the part of the FDA that oversees drug safety is within that division. So there's a structural problem. There's not enough separation in the FDA from the drug companies.

(END VIDEO CLIP)

O'BRIEN: So what about that relationship? Drug companies need the FDA's blessing. The FDA needs the drug company's money. That has been business as usual for quite some time now. There's talk now that a change may be due. Here is medical correspondent Elizabeth Cohen.

(BEGIN VIDEOTAPE)

ELIZABETH COHEN, CNN MEDICAL CORRESPONDENT (voice-over): The Vioxx hearings have left many people wondering how could a drug that causes heart attacks get approved by the Food and Drug Administration? Doesn't the United States have the best, most rigorous drug approval process in the world? The answer to that question has to do with a common misperception.

Many people think it is the FDA that conducts studies on drugs before they go on the market. In fact, the pharmaceutical companies do the studies on their own drugs. The FDA just reviews their data. And more and more observers, such as Dr. Jerry Avorn, author of the book "Powerful Medicines" thinks this system doesn't make much sense.

DR. JERRY AVORN, HARVARD MEDICAL SCHOOL: I think we need to have a more vigilant and aggressive FDA.

COHEN: One problem, he says, the salaries of the FDA reviewers are paid in part by the drug companies. The pharmaceutical industry spends hundreds of millions of dollars on so-called user fees to the FDA. And some say that makes for too cozy of a relationship.

AVORN: And it really needs to be a tough agency that is going to really ask some very demanding questions because we're talking about chemicals that people put into their body that can alter their health for good or for ill.

ALAN GOLDHAMMER, PHARMACEUTICAL IND. SPOKESMAN: We have seen these allegations of the coziness between the industry and the Food and Drug Administration. We think that they really are not true.

COHEN: In fact, the pharmaceutical industry says...

GOLDHAMMER: The process for approving new drugs by the Food and Drug Administration is working quite well.

COHEN: The industry points out that it spends years testing each drug on animals and then on humans. And the FDA then takes about a year to review those studies and often asks for even more data. But others say that pulling Vioxx and other drugs off the market because of safety worries is proof that somehow somewhere the system is falling short.

Elizabeth Cohen, CNN, Atlanta.

(END VIDEOTAPE)

O'BRIEN: Keep it right here on CNN for more on Vioxx, the FDA, it's relationship with drugmakers and the blame game. All of that in our next our of LIVE FROM.

LIN: All right. Meanwhile, a quick look at what is making news across America right now. Mental issue? Road rage? Who knows. Police are trying to piece together what led a man to walk into the Gateway Mall in St. Petersburg, Florida, with a gun yesterday. He opened fire, killing two people, wounding a third, then turned the gun on himself. Investigators are stumped.

Bizarre. A Massachusetts woman on her deathbed confesses to a killing and points police to the body. The victim, her husband, 14 years ago. The confessor died last week. Police did find the body. Identification is still forthcoming.

A hearing today in a suburban Atlanta courtroom for two 13-year- old girls. The charge is assault with intent to commit murder. Authorities say the two teens served up some poison-laced cake to a dozen classmates, all of whom got sick.

And is this a deadly weapon? Well, it almost was. Police say a car load of teenagers threw a 20-pound frozen turkey into Long Island traffic. It went through the windshield of another car and hit the driver in the face. A woman is now in critical condition. Six teenagers arrested and the list of charges is pretty long.

This may be hard to believe as well, but there is a downside to being the richest man in the world. Poor Bill Gates. Also, he has the uneviable reputation of being the most spammed guy in the world. He's inundated with up to 4 million -- that's right, you heard me, 4 million e-mails every day, most of them junk. But, unlike most of us, the software magnate has almost an entire department to filter out unwanted e-mails. A jobs program.

All right. Bill Gates can't be very happy about that either, but did you know that a browser war was being waged? The diehard Netscapers and Explorer fans among you probably do know there's a new kid in town and it is taking aim at the big two.

Daniel Sieberg is our technology correspondent, he's here to smarten us up on Firefox and why we're even talking about it today. Isn't more better, Daniel?

DANIEL SIEBERG, CNN TECHNOLOGY CORRESPONDENT: Well, to some people it definitely is, Carol. And the first rounds have been fired in this latest browser war. And the question now is how it will reshape the online landscape. Now let's take short trip back in time. Go with me here if you will.

Remember, Netscape? It is still around. It's part of our parent company, Time Warner. But you'll recall that Netscape used to dominate the browser market in the early days of the Web. And along came Bill Gates and Microsoft. Some years passed. We had some rather controversial bundling of software from Microsoft. And by the late 1990s, Internet Explorer had reduced Netscape to really just a few dedicated users.

OK. Fast forward to today and the fox in Microsoft's henhouse. Firefox is a new browser from a nonprofit offshoot of Netscape called Mozilla. It promises to be faster, easier and safer, when we're talking about viruses and spyware, than IE, or Internet Explorer. Oh, and by the way, it is free.

But it still isn't perfect with every Web site out there. And that's because some places designed their pages to be read on Internet Explorer. So some growing pains to work out. Is Microsoft taking notice? You bet. Are they worried? Well, they're not exactly pulling out all the stops, let's say, but it has been a long time since the company started firing shots in the browser market.

Microsoft is a huge target. So let's lay out the battle lines here. Let's see how are drawn. Microsoft still with a huge share of the market, obviously at 93 percent. The overwhelming majority of people out there use Internet Explorer. But Firefox, I know 3 percent sounds small, but Firefox claims that about 4 million people have downloaded their software in the last month or so and that number is still going up.

Netscape hanging around. Safari, which is Apple's browser software, and Opera, which is actually based in Norway, they are also vying for more of the cybersurfing share. Netscape has a new product coming out, by the way, and Safari getting some good reviews.

At this point the question isn't so much will Microsoft win but how will this competition force some changes in how we surf the Web. And you know, some experts say that's overdue. They say that Microsoft got a bit complacent after IE dominated the scene. It's time that another company came along to get things fired up and that may be Firefox -- Carol.

LIN: That's why we like competition, America.

SIEBERG: Exactly. The consumer always wins.

LIN: There you go, hopefully. Daniel, thank you.

O'BRIEN: Excelling at your job and your life? Up next on LIVE FROM, how to find profit, passion and purpose while on the road to success.

LIN: All right. Later, the princely pupil, a rare glimpse at college life of Prince William, which is about to come to an end.

(COMMERCIAL BREAK)

O'BRIEN: All right. Ever thought of your job as an endless cycle of paydays, a soloist climb to the top, making your deal with the devil? Everyday. Not really.

Kevin Salwen and Anita Sharpe are here to talk about how to add a little punch to your paycheck, so to speak. They are the founding editors of a magazine called "Worthwhile." It's a new personal business magazine, focusing on the quest for heart and soul of work. It just hit newsstands. You might not be able to find it, because apparently, it's flying off the shelves. Welcome. Glad things are going well.

ANITA SHARPE, "WORTHWHILE" MAGAZINE: Thank you. Thank you.

O'BRIEN: Glad things are going well.

SHARPE: They are. We're really encouraged.

O'BRIEN: Tell us, just give us a quick backstory on this, the idea of the magazine. You obviously saw a little niche here. Give people a sense of what the magazine was all about and where the idea came from.

SHARPE: The idea, sort of the soundbite for the magazine really is, it's about enlightened leadership and impassioned careers, and Kevin and I starting talking about it more than a year ago, and looking around and saying, there's really not a magazine that addresses what we do where we spend more than half of our lives, which is at work, and they're plenty of business magazines, but this is really more of a -- we like to call it sort of a career life summit.

O'BRIEN: You're both business journalists, "Wall Street Journal" background, and publications like "The Wall Street Journal" cover the business world wonderfully, but they miss this aspect of it, don't they?

KEVIN SALWEN, "WORTHWHILE" MAGAZINE: Well, you mentioned in your intro, it's really about heart and soul. And think about it, we wake up, we spend 50 hours a week doing our careers, doing our work. It's intensely important to us. We don't want to read profiles of other companies. We want to read things that go right to our core, and that's what "Worthwhile" is really focusing on.

O'BRIEN: Now, you -- on the cover here, you have the guys, the "life is good" guys. How are you selecting people? What are you looking for as you look at people to put in for content into your magazine?

SHARPE: Well, we're looking for people whose stories are likely to inspire, stories about people who are doing things both inside big corporations, outside, who are loving what they do. So you can read the story and think, ah, that person is who I want to be. And also, we're trying to find real people, people that not just sort of pie-in- the-sky type careers, but real stuff.

O'BRIEN; That's a good point, because I'm sure there are a lot people who would pick up this magazine, Kevin, in the Dilbert world, if you will, and say, you know, that's great, that sounds like fun, but I can't get there from here.

SALWEN: Right, and we understand that in every single, magazine we have to have a string of practical ideas that people can execute today, tomorrow, this week, whatever. And so, in addition to the inspiration, yes, we have these role models out there, that are out there that are out there sort of, you know, hey look, I can beat that, or I can emulate that. But at the same time, we have to give people real tools to be able to do it. There's a section in the magazine actually called "Toolbox" that is all about that.

O'BRIEN: All right, we selected a couple toolbox items, as a matter of fact. You have segued beautiful to this segment.

SALWEN: I'm good at that.

O'BRIEN: Focusing our passion is one of them, and it gives a series of steps. Here are the top six, create your own compass. What does that mean, create your own compass?

SALWEN: Well, it's really digging down into sort of the things that trigger you. What are things that actually -- Kurt Rosengrand (ph), who wrote that piece, focuses on what he calls the passion core. And it's really starting to examine, what are the things that motivate me. You do it so easily in your personal life and in your social life. You automatically gravitate to the things that inspire you and set you on fire. Why not do it in the 50 hours a week you're working?

O'BRIEN: And can you say "passion core" on TV? Is that OK?

SALWEN: It's just did.

O'BRIEN: It's cable.

All right, sculpt and scan, what is that all about?

SHARPE: Sculpt and scan. You really have to look at the broad field of what's out there, but at the same time, you have to sort of narrow it down. You have to keep both perspectives in mind all of the time. You have to be picking up clues, and at the same time, you have to be focusing.

O'BRIEN: Focusing is one of the hardest things, I think, for a lot of people. Now where is the fit? What does that mean?

SALWEN: Well, it's very easy for me to say, you know, I want to be a NASA astronaut, but I really don't have the tools to do that. And you've got to be able to sort of be practical about this. You know, what we were talking about before, that practicality element. If you're going to do something that really sets you on fire, it's got to be something within your core.

O'BRIEN: And having seen you on the (INAUDIBLE), I do know you will never make it to the astronaut car. OK, whittling them down. That seems fairly self evident, but going about that, I guess, is the key, and finding the tools and sort of figuring out what's most important to you is the hardest part, right?

SHARPE: Right, right, well, you have to take all of these clues, and then you have to fit them to your talents, and you have to -- and so you have to take 12 things and really get it down, ultimately, to one or two or three.

O'BRIEN: And then map it and hit the road. Those seem self- evident. I guess the key here is that what you have to view this pursuit as a career unto itself, don't you? SHARPE: Right, right. Absolutely. I mean, it's not like you have to quit your job and devote full time to it, but it's an important thing. You have to...

O'BRIEN: Don't be so accidental about it, in other words.

SALWEN: No, you know, great things happen accidentally when you're in the right place, and when you've done the work to get you to the point where you can structure, you know, your own career, things come to you, and all of a sudden, hey, it's the great opportunity, and you've got it.

O'BRIEN: Chance favors of the pared mind, I think is the expression.

SHARPE: Absolutely.

O'BRIEN: Anita Sharpe -- I didn't make that up. Anita Sharpe, Kevin Salwen. The magazine is "Worthwhile," and if you see it on a newsstand, well worth your while. We invite you to pick it up and check it out. Thanks for your time. Good luck with the magazine.

SHARPE: Thank you.

O'BRIEN: All right. He's just a year away from entering public life. Up next on LIVE FROM, a look at college life for Prince William in a rare interview.

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LIN: The second in line to the British thrown would be scanning the help-wanted ads next year. Prince William, son of Charles and Diana, finishes university in a few months, but has yet to decide what to do with himself.

CNN's Diana Muriel has been taking a look at his options.

(BEGIN VIDEOTAPE)

DIANA MURIEL, CNN ANCHOR (voice-over): An ordinary student on his way to lectures, but Prince William is no ordinary student. He is second in line to the British throne. These pictures offer a glimpse of the young prince's life at university. Like many students, he's behind in his courses.

UNIDENTIFIED MALE: And what about the glacial essay?

PRINCE WILLIAM: Yes, that hasn't materialized at all yet. I've done a few bits of reading.

MURIEL: Still, his geography tutor admires his princely pupil.

CHARLES WARREN, PRINCE WILLIAM'S TUTOR: He's worked really hard not to let his presence disrupt his fellow students existence, and keep a low profile, pull his weight and become one of the crowd. So no one lifts an eye brown these days when he walks around. MURIEL: That's not entirely true. William still turns heads, but he has a strong and supportive group of friends.

Next May, the 22-year-old prince leaves the same confines of his Scottish university. William admits he hasn't decided what he wants to do, but the army is a possibility.

PRINCE WILLIAM: If I was going join the army, which out of all the armed forces, it would be probably my favorite, or to do something different, (INAUDIBLE) to join the Navy, and (INAUDIBLE) something different, and the army, it's obviously a lot more in the spotlight of (INAUDIBLE).

MURIEL: What he does know is that life outside of university will never be as private again, and that could be tough.

PRINCE WILLIAM: Deep down, I have a, you know, pretty normal life. I'm not really taken for sort of fanfare and excitement and things like that, but I rise to the occasion when I need to.

MURIEL: William plans to take time off to travel when he leaves school next year, while he decides what to do next.

Diana Muriel, CNN, London.

(END VIDEOTAPE)

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LIN: Also coming up in the second hour of LIVE FROM, academic achievement. This woman was one of the top in her class, but now, more than 50 years later, she finally gets the credit she deserves.

LIVE FROM's hour of power begins right after this.

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